Glossary entry (derived from question below)
English term or phrase:
2’-O-alkyl analogs
Polish translation:
analogi 2’-O-alkilowe
Added to glossary by
Polangmar
Nov 29, 2012 20:50
11 yrs ago
English term
2’-O-alkyl analogs
English to Polish
Medical
Medical: Pharmaceuticals
Opis metod polepszania przenikania leków przez sciany jelita
Kontekst:
The polynucleotides may be chemically modified. This may enhance their resistance to nucleases or may
enhance their ability to enter cells. For example, phosphorothioate oligonucleotides may be used. Other deoxynucleotide analogs include methylphosphonates, phosphoramidates, phosphorodithioates, N3’P5’-phosphoramidates and oligoribonucleotide phosphorothioates and their 2’-O-alkyl analogs and 2’-O-methylribonucleotide methylphosphonates. Alternatively mixed backbone oligonucleotides (MBOs) may be used.
The polynucleotides may be chemically modified. This may enhance their resistance to nucleases or may
enhance their ability to enter cells. For example, phosphorothioate oligonucleotides may be used. Other deoxynucleotide analogs include methylphosphonates, phosphoramidates, phosphorodithioates, N3’P5’-phosphoramidates and oligoribonucleotide phosphorothioates and their 2’-O-alkyl analogs and 2’-O-methylribonucleotide methylphosphonates. Alternatively mixed backbone oligonucleotides (MBOs) may be used.
Proposed translations
(Polish)
| 4 +3 | analogi 2’-O-alkilowe |
Polangmar
|
Change log
Nov 30, 2012 22:23: Polangmar Created KOG entry
Proposed translations
+3
12 mins
Selected
analogi 2’-O-alkilowe
Dosłownie.
4 KudoZ points awarded for this answer.
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