... यह होटल उस संपर्क केंद्र के बीचोंबीच मौजूद है जो मिलान व लुगानो (स्विट्ज़़रलैंड) के मध्‍य में स्थित है...


It is more than just intersection. I think it is more of a meeting point of two different cultures. संपर्क स्‍थल may also be used.

I think I get what you are aiming at. The dictionary gives the following meanings for crossroad:

crossroads

Plural form of crossroad.

A place where one road crosses another; an intersection of two or more roads.
(by extension) A centrally located position
(by analogy) A decision point; a turning point or opportunity to change direction, course, or goal.
(nonstandard) A fork in the road.

(http://en.wiktionary.org/wiki/crossroads)

You have in mind the second meaning above.

Well, in my opinion, there could be various ways of conveying this meaning in Hindi. Here are some options that you can consider and choose from:

केंद्रीय भाग/केंद्र
हृदय स्थल
मुख्य विनिमय केंद्र
शहर के ठीक मध्य में स्थित
शहर के प्रमुखतम भाग में स्थित

In olden times, suhc a place would be called a सराय but this word would be inappropriate in your context.

Hope any of the above suggestions would be useful, or you could think along those lines and arrive at your own solution.

संधि स्थल, मिलन बिंदु, मिलन स्थल

यहां दो स्थानों के बीच मौज़ूद महत्वपूर्ण संधि स्थल के मध्य में स्थित होटल की चर्चा है। यह संधि स्थल सांस्कृतिक आधार पर भी हो सकता है और भौगोलिक आधार पर भी।

In my opinion here the word crossroad is meant to be 'Doraha', or 'golchakkar'as it is connecting two roads.....